This paper will shed light on the nature of the disease, its etiology, its agents and the current ways of treatment and prevention. When left untreated, staph bacteria can find a way into the body through open wounds, needles and any other element which penetrates the epithelium that protects us from the outside. After penetrating the body, a stage known as invasive MRSA, the staph enters the blood circulation, dissolve many white blood cells and may cause severe infections, primarily Bacteremia, Pneumonia, Cellulitis, Osteomyelitis, Endocarditis and Septic shock Klevens et al. MRSA was first reported in Britain inwhen researchers identified that Staphylococcus bacteria developed resistance to methicillin and cloxacillin, two powerful antibiotics from thr penicillin family that were used against them.
MRSA is a type of S. In this study isolation of Methicillin-Resistant Staphylococcus aureus MRSA strains was done from various surgical and accidental wounds. The rate of prevalence of MRSA was found to be Staphylococcus aureus is the most common and ominous staphylococcal bacteria in this family.
Durai, R., Ng, P., & Hoque, H. (). methicillin-resistant staphylococcus aureus: an update. Association of periOperative Registered Nurses Journal, 91(5), Summary of Article: the authors of this article provide the latest overview regarding methicillin-resistant staphylococcus aureus (MRSA), a serious threat to the community . Methicillin Resistant Staphylococcus Aureus Essay Words | 7 Pages. healthy, asymptomatic persons (i.e., carriers) and can cause infections with clinical manifestations ranging from pustules to sepsis and death. Most transmission occurs through the contaminated hands of a person infected with or carrying S. aureus. The purpose of the research conducted was to evaluate patient opinion on the subject and about asking healthcare professionals to wash their hands before a procedure and to explore if methicillin-resistant Staphylococcus aureus (MRSA) status and access to patient information about infection control would influence the patients anxiety about asking.
Tissues can be infectious with S. This rupture can cause different types of infections including blisters and abscesses. Due to their pathogenic nature staphylococci often hemolyze blood, coagulate plasma and produce a variety of extracellular enzymes and toxins. The more dangerous forms of S.
The main cause of these infections are the toxins produced by staphylococci. Post-surgical infections accounts for approximately one-fourth of all hospital acquired infections.
Many risk factors for S. Throughout the world, particularly in developing countries burn wounds remains an important problem of public health associated with diseases, long-term disability and mortality Othman and Kendrick, ; Othman and Kendrick, The burned dead moist tissues, along with damaged tissues, provide a nutrient medium which will favor the growth of a many species of bacteria.
In a definite part of burns this type of control of bacteria causes septicemia and death Nakhla and Sanders, Diabetic foot infections caused by MRSA are linked with lethal results, i.
In diabetic foot infections MRSA infection is common and is associated with increased time of healing with antibiotic treatment Tentolouris et al. In developing countries like Pakistan MRSA infection has become a major ailment in hospitals and they have been a cause of increasing cost, disease rate and deaths associated with surgical operations.
The sensitivity shown by staphylococci against antimicrobial drugs is variable. Staphylococcal resistance falls into many classes.
For methicillin resistance the responsible gene mecA exists on the chromosomes. The resistance mechanism is related to lack of inaccessibility of certain penicillin-binding proteins PBPs in the organisms.
A protein called as PBP2a, possess a less attraction to antibiotics, encoded by a mecA gene on chromosome Cook, Increased synthesis of cell wall and modification of cell wall are associated with resistance mechanism and Van genes present in enterococci are not responsible for this.
Since first reported in Jevons,number of diseases, death rate and treatment expenses associated with infection of skin and soft tissue, pneumonia associated with ventilator, bacteremia and many other nosocomial and community infections has been gradually increasing.
Treatment and managerial costs associated with MRSA infections continue to increase whereas the number of effective antibiotics remains relatively constant Krikland and Adams, American Academy of Pediatrics, Transmission of MRSA occurs by direct contact to a colonized carrier.
The main source of spread is from patient to patient on the hands of hospital staff. Health care workers HCWs possibly related to principles of hygiene regarding uniforms, equipment sterilization and washing, transmitting the pathogenic organisms on moving from patient to patient Elmanama et al.
Use of different types of antibiotics especially during long-term treatment and other factors related to MRSA colonization are; long-term hospital stay, burns, surgical wound care Sanford et al.
All over the world, increased prevalence and antibiotic resistant bacteria are the issues, faced by the hospitals. For public health and hospitals, antimicrobial resistance is becoming a matter of great concern. Moreover, numerous reports of completely resistant S. Prevalence of MRSA infection is continuously elevating in many countries and in some hospitals Voss and Doebbeling, In the developing countries like Nigeria the antibiotics are used without prescription of doctor and no control measures are adopted having no regulatory policies in this respect has make less effective antibiotics for the treatment of infections of S.
Onwubiko and Sadiq, Keeping in view the importance of the subject, present study has been planned to achieve the following objectives: Isolation, Identification and Molecular characterization of indigenous MRSA strains from accidental and surgical wounds.
The cause of wound infections and bacteremia in burned patients was studied for a period of 8 years Both in wound samples and blood cultures the prevalence of staphylococci was studied.
These results shows the need of quick steps to control the more spread of MRSA infections in burn units. Against most antibiotics the methicillin resistant strains were found highly resistant as compared to isolates which were methicillin sensitive.Methicillin Resistant Staphylococcus Aureus Staphylococcus aureus bacteria, commonly known as staph, are very common.
It is "a spherical gram-positive parasitic bacterium of the genus Staphylococcus, usually occurring in grapelike clusters and . Methicillin-resistant staphylococcus aureus: the problem reaches paediatrics. Archives of Disease in Childhood, 89 (2), In this article, the author stated that Methicillin-Resistant Staphylococcus Aureus are commonly not just resistant to methicillin and other Î²-lactam antibiotics, but they are also resistant to other classes of antibiotics.
Methicillin Resistant Staphylococcus Aureus Essay Words | 7 Pages. healthy, asymptomatic persons (i.e., carriers) and can cause infections with clinical manifestations ranging from pustules to sepsis and death. Most transmission occurs through the contaminated hands of a person infected with or carrying S.
aureus. The topic for this piece of work is Methicillin-resistant Staphylococcus aureus (MRSA). This area of research was chosen due to the science and medical aspect behind this very interesting topic.
MRSA is a topic of great importance for the general public but also for health professionals, e.g. nurses and doctors. Methicillin Resistant Staphylococcus Aureus Staphylococcus aureus is an important and common pathogen in humans.
It is found in the nose or on the skin of many healthy, asymptomatic persons (i. e., carriers) and can cause infections with clinical manifestations ranging from pustules to sepsis and death. MRSA in the Community According to Mosby’s Medical, Nursing, and Allied Health Dictionary (), Methicillin-resistant staphylococcus aureus (MRSA), is a gram positive bacterial that is normally found on the skin and in the throat, and is a life threatening staphylococcal infection that may arise within hospitals, and “is frequently responsible .